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Tirzepatide and semaglutide, the active ingredients in Mounjaro and Ozempic, are also available under different brand names and for different indications: Zepbound (tirzepatide) is approved for weight management in people with obesity or overweight with a weight-related health condition (such as high blood pressure)

Inject once daily, at any time of the day, into the abdomen, thigh, or upper arm

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Contraindications Do Not Use If You Have uncontrolled hypertension Have known cardiovascular disease Have a history of hypersensitivity to bremelanotide or any component of the formulation Are pregnant or planning to become pregnant Warnings and Precautions Transient increase in blood pressure and decrease in heart rate: Bremelanotide causes a transient increase in blood pressure (average of 1.9/1.7 mmHg systolic/diastolic, with larger increases in some patients) and a decrease in heart rate following administration

In addition, in a previous animal model, liraglutide pretreatment attenuated LPS-induced acute lung injury in mice

10.1523/JNEUROSCI.5610-12.2013 J